This collection includes correspondence, news clippings, ephemera, and photographs from Betty Lank's family and life. The collection includes items relevant to her nursing career including an autograph book from fellow colleagues and her nurse anesthetist certificate. A collection of photographs from Betty Lank's relatives is also included. There is little information with the images to help understand their association with Lank herself. There are a few photographs of Lank, as well as correspondence written to her from colleagues. Also included, are her notes from a presentation she gave about pediatric anesthesiology.

The collection focuses largely on Princess Lilian of Belgium (see biographical note). Items relating to this include photographs from Lilian's life as well as newspaper clippings. The photographs depict travels (including a trip to the Congo and hunting expeditions) of Princess Lilian and her family (especially her husband King Leopold III, but also including her three children: Prince Alexander, Princess Marie-Christine (b.1951), and Princess Marie-Esmeralda (b.1956)). The images display Lilian’s devotion to cardiac research.

The collection also highlights Betty's close relationship with fellow nurse and roommate, Marie Dresser. Correspondences from Princess Lilian to Marie Dresser and Betty Lank (simultaneously) address the relationship between the three women.